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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPR1 All Species: 19.39
Human Site: S332 Identified Species: 47.41
UniProt: Q14643 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14643 NP_001093422.1 2758 313945 S332 E C L E F Q P S V D P D Q D A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102937 2700 308048 K330 R D A Q N E G K N V R D D H P
Dog Lupus familis XP_851008 2757 314037 S332 E C L E F Q P S V D P D Q D A
Cat Felis silvestris
Mouse Mus musculus P11881 2749 313179 S332 E C L E F Q P S V D P D Q D A
Rat Rattus norvegicus P29994 2750 313246 S332 E C L E F Q P S V D P D Q D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001167530 2712 309042 S332 D D Q E C Q S S Q D P E Q D A
Frog Xenopus laevis NP_001084015 2693 306654 E317 T G H Y L A A E I D A E P D A
Zebra Danio Brachydanio rerio XP_001921194 2691 306311 S332 E S Q E S R S S L D S E H E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29993 2838 319089 D352 H L G D C S K D S G L S C S T
Honey Bee Apis mellifera XP_392236 2749 311321 D338 K G K R G K I D I S S K E T F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 68.8 98.6 N.A. 98.2 98.2 N.A. N.A. 93.6 87.8 85.4 N.A. 58.5 62.5 N.A. N.A.
Protein Similarity: 100 N.A. 80.8 99.2 N.A. 99 98.9 N.A. N.A. 96.1 92.3 91.3 N.A. 72.1 76.7 N.A. N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 100 N.A. N.A. 53.3 20 33.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 N.A. 20 100 N.A. 100 100 N.A. N.A. 66.6 33.3 60 N.A. 6.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 10 0 0 0 10 0 0 0 70 % A
% Cys: 0 40 0 0 20 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 20 0 10 0 0 0 20 0 70 0 50 10 60 0 % D
% Glu: 50 0 0 60 0 10 0 10 0 0 0 30 10 10 0 % E
% Phe: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 20 10 0 10 0 10 0 0 10 0 0 0 0 0 % G
% His: 10 0 10 0 0 0 0 0 0 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 0 0 10 0 20 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 10 10 10 0 0 0 10 0 0 0 % K
% Leu: 0 10 40 0 10 0 0 0 10 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 40 0 0 0 50 0 10 0 10 % P
% Gln: 0 0 20 10 0 50 0 0 10 0 0 0 50 0 0 % Q
% Arg: 10 0 0 10 0 10 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 10 0 0 10 10 20 60 10 10 20 10 0 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 0 0 0 0 0 0 0 0 40 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _